Enzymes

EFSA Concludes No Safety Concerns For Food Enzyme Glucan 1,4‑α‑Maltotetraohydrolase From GM Bacillus Licheniformis DP‑Dzf95

EFSA has issued a positive safety opinion for the food enzyme glucan 1,4‑α‑maltotetraohydrolase, clearing a major technical hurdle for its use in EU food manufacturing. This assessment signals a clear path toward formal market authorization, allowing manufacturers to plan for its integration into processing while maintaining safety and allergenicity standards.

9 Apr 2026, 17:36efsa.europa.euEuropean Union

EFSA Receives Application to Modify Glutaminase Food Enzyme (Bacillus licheniformis, NZYM-JQ)

EFSA has commenced the safety assessment for a modification to the authorized food enzyme glutaminase produced by Bacillus licheniformis. Manufacturers should track this assessment as it may lead to updated specifications for enzyme preparations used in food processing.

5 Apr 2026, 18:50open.efsa.europa.euEuropean Union

EU EFSA Panel Evaluates Extension Of Use For Food Enzyme Glucan 1,4‑α‑Maltohydrolase (NZYM‑SD)

EFSA has issued a positive safety opinion for extending the use of the food enzyme glucan 1,4-α-maltohydrolase to five food manufacturing processes, including plant-based milk analogues. This assessment clears a major technical hurdle for expanded market access and provides regulatory certainty for manufacturers using this enzyme in diverse food categories.

2 Apr 2026, 17:04efsa.onlinelibrary.wiley.comEuropean Union

Japan MAFF Amends Pesticides Control Act Ministerial Standards for Phytase-Based Feed Calculations

Japan's MAFF has updated the Pesticides Control Act ministerial standards to align phytase-based feed calculation cross-references with current feed additive regulations, effective March 30, 2026. This technical correction ensures regulatory consistency for compound-feed formulations, requiring manufacturers to update internal compliance documentation and calculation tools.

1 Apr 2026, 18:26kanpo.go.jpJapan

EFSA Consults on Extension of Use of Alpha-Amylase Food Enzyme (GM Bacillus licheniformis NZYM-AV)

EFSA is consulting on the expanded use of alpha-amylase derived from genetically modified Bacillus licheniformis through April 2, 2026. Successful authorization would broaden market access for this specific enzyme, necessitating updates to food formulation compliance and labeling strategies.

28 Mar 2026, 20:30open.efsa.europa.euEuropean Union

EFSA Consults on Extension of Use for Food Enzyme Endo-1,4-β-Xylanase (Bacillus licheniformis NZYM-CE)

EFSA is consulting on extending the authorized uses for the food enzyme endo-1,4-β-xylanase (produced via GM strain) until April 3, 2026. Food and enzyme manufacturers should assess the proposed extensions to ensure alignment with product development and future EU market access requirements.

28 Mar 2026, 20:30open.efsa.europa.euEuropean Union

EFSA Adopts Opinion on Extension of Use of Cellulase Food Enzyme From GM Trichoderma reesei AR-852

EFSA published a positive safety opinion on March 26, 2026, supporting the extension of use and revised levels for the cellulase food enzyme from GM Trichoderma reesei. This assessment clears the path for the European Commission to formally authorize expanded applications in food and beverage processing, including cereals, brewing, and juices.

28 Mar 2026, 18:21doi.orgEuropean Union

EU EFSA Updates Safety Evaluation Of Cellulase Food Enzyme From GM Trichoderma reesei AR-852

EFSA has issued a positive safety opinion for the expanded use and revised concentration levels of cellulase from GM Trichoderma reesei in food manufacturing. This scientific endorsement facilitates the formal EU authorization process, potentially allowing broader application of the enzyme in food processing operations.

28 Mar 2026, 17:03efsa.europa.euEuropean Union

EU EFSA Registers Intake of Application to Modify Phospholipase C Food Enzyme (Bacillus licheniformis NZYM-VR)

EFSA has formally registered an application to modify the existing authorization for the food enzyme phospholipase C (produced by Bacillus licheniformis). This signals a forthcoming safety and technical review that may eventually alter market access conditions or usage specifications for food and beverage manufacturers using this enzyme.

28 Mar 2026, 17:01open.efsa.europa.euEuropean Union

EFSA Intake of Application for Alpha-Amylase Food Enzyme From GM Komagataella Phaffii

EFSA has initiated the safety assessment process for a new alpha-amylase food enzyme produced from a genetically modified strain of Komagataella phaffii. Manufacturers should monitor this dossier as its eventual approval will expand the list of authorized food enzymes and define specific purity and safety criteria for market access.

28 Mar 2026, 09:36open.efsa.europa.euEuropean Union

South Korea MFDS Consults On Draft Safety Review For GM Microorganism-Derived Cellulase Food Additive

South Korea's MFDS is consulting on a draft safety assessment for a GM microorganism-derived cellulase food additive through April 2026. This process signals a potential regulatory path for new biotech-derived ingredients, requiring manufacturers to ensure scientific data aligns with national food safety standards.

27 Mar 2026, 20:06mfds.go.krSouth Korea

EFSA Consultation on Authorisation of Endo-1,4-Beta-Xylanase Feed Additive (Trichoderma reesei KCCM 8037) for All Pigs and Avian Species

EFSA is consulting on the authorization of endo-1,4-beta-xylanase as a feed additive for pigs and poultry through late March 2026. This marks a key step in the market entry process, requiring stakeholders to validate safety and efficacy data before final EU-wide approval.

27 Mar 2026, 07:53open.efsa.europa.euEuropean Union

EU EFSA Extends Clock Stop In Risk Assessment Of Cellulase And Hemicellulase Food Enzyme From Aspergillus luchuensis AE-C

EFSA has extended the risk assessment for cellulase and hemicellulase food enzymes from Aspergillus luchuensis, delaying the indicative completion date to April 2028. This extension prolongs regulatory uncertainty for the food industry, necessitating adjustments to innovation pipelines and market entry timelines for these specific enzyme preparations.

27 Mar 2026, 07:48open.efsa.europa.euEuropean Union

EFSA Ongoing Risk Assessment On Extension Of Use Of Bacillolysin Food Enzyme (Bacillus Amyloliquefaciens HPN 131)

EFSA is evaluating an application to extend the authorized uses of the food enzyme bacillolysin, with a final scientific opinion due by September 2026. Successful assessment will likely lead to expanded market access and updated compliance requirements for food processors using this enzyme in the EU.

27 Mar 2026, 07:02open.efsa.europa.euEuropean Union

EU EFSA Registers Follow-Up Alpha-Amylase Food Enzyme Application (EFSA-Q-2026-00173)

EFSA has commenced the safety assessment for a follow-up application to authorize alpha-amylase derived from a genetically modified strain. This evaluation is a mandatory precursor to market access, requiring food producers to monitor the outcome for future formulation and compliance planning.

26 Mar 2026, 19:29open.efsa.europa.euEuropean Union

EFSA Ongoing Risk Assessment of Extension of Use of Alpha-Amylase Food Enzyme (Bacillus licheniformis NZYM-AN)

EFSA is reviewing an application to extend the authorized uses of the alpha-amylase food enzyme, with a scientific opinion expected by November 2026. Success will broaden formulation flexibility for food producers, while the assessment process signals continued scrutiny of enzymes derived from genetically modified organisms.

26 Mar 2026, 19:14open.efsa.europa.euEuropean Union

EFSA Launches Public Consultation on Glutaminase Food Enzyme From GM Bacillus subtilis Glu3-3

EFSA is consulting on the safety of glutaminase from genetically modified Bacillus subtilis, with a final risk assessment expected by June 2026. This assessment is a critical step for the legal authorization of this enzyme, impacting future formulation options and supply chain compliance for food processors.

26 Mar 2026, 11:31open.efsa.europa.euEuropean Union

EU EFSA Receives Application to Authorise Transglutaminase Food Enzyme

EFSA has initiated the suitability check for the authorization of transglutaminase as a food enzyme for inclusion in the EU Union list. This marks the start of a formal risk assessment process that will determine future market access and permissible conditions of use for food manufacturers.

24 Mar 2026, 11:39open.efsa.europa.euEuropean Union

EU EFSA Registers Intake of Application to Modify Food Enzyme NZYM-ST (Beta-Glucanase, Xylanase, Cellulase)

EFSA has initiated the assessment of an application to modify the authorization for the food enzyme preparation NZYM-ST (beta-glucanase, xylanase, and cellulase). This development signals potential updates to EU market authorization conditions, requiring manufacturers to track the assessment for future compliance adjustments.

24 Mar 2026, 11:39open.efsa.europa.euEuropean Union

EFSA Opens Consultation On Authorisation of Phospholipase A1 Food Enzyme From Genetically Modified Komagataella phaffii (Strain PHLSC)

EFSA has launched a public consultation on the authorization of a new phospholipase A1 food enzyme derived from genetically modified sources, with comments due by March 24, 2026. This regulatory milestone is a prerequisite for EU market entry, requiring food processors and biotech firms to monitor the assessment outcome for future product development and compliance.

21 Mar 2026, 15:50open.efsa.europa.euEuropean Union