Enzymes

EU EFSA Consults On Animal Rennet (Chymosin And Pepsin A) From Bos Taurus As New Food Enzyme

EFSA is conducting an ongoing risk assessment, including public consultation, on an application to authorise animal rennet containing chymosin and pepsin A from Bos taurus as a new food enzyme in the EU. If approved, this enzyme could broaden authorised processing options for dairy manufacturers under the EU food enzymes regime, so operators should track the EFSA opinion and subsequent authorisation decision within the current 2026 deadline window.

12 May 2026, 12:49open.efsa.europa.euEuropean Union

EFSA Continues Risk Assessment of 6‑Phytase Feed Additive for Laying Hens

EFSA is still assessing ADISSEO’s application to authorise a 6‑phytase feed additive for laying hens and minor poultry under the EU Feed Additives Regulation, with its internal deadline now set for 20 September 2026. This extended timetable signals that any EU decision on this specific enzyme product is unlikely before late 2026, giving feed additive suppliers and poultry producers more time to plan formulations and supply scenarios.

5 May 2026, 06:46open.efsa.europa.euEuropean Union

EU EFSA Consults on Authorisation of Trypsin and Chymotrypsin (Porcine Pancreas) as New Food Enzyme

EFSA is running an EU-level public consultation, closing 17 November 2026, on an application to authorise trypsin and chymotrypsin from porcine pancreas as a new food enzyme under the EU Food Enzymes Regulation. Food and beverage manufacturers using enzymatic processing should track this dossier as a potential new tool that could widen formulation options while creating specific conditions and documentation expectations for compliant use across the EU single market.

4 May 2026, 20:01open.efsa.europa.euEuropean Union

EFSA Opens Consultation on Follow-Up Opinion for Endo-1,4-Beta-Xylanase From Trichoderma citrinoviride Strain 278

EFSA has opened a short public consultation (8–29 April 2026) on a follow-up opinion for the food enzyme endo-1,4-beta-xylanase produced by non-GM Trichoderma citrinoviride strain 278. Food enzyme manufacturers and food producers using xylanase preparations should track and, where relevant, contribute to this process, as the resulting opinion may shape future EU authorisation conditions and use requirements.

26 Apr 2026, 16:56open.efsa.europa.euEuropean Union

EFSA Ongoing Risk Assessment Of Glucoamylase (Glucan 1,4-α-Glucosidase, CAS 9032-08-0) As Food Enzyme

EFSA is conducting an ongoing risk assessment of a new food enzyme application for glucoamylase (glucan 1,4-α-glucosidase, CAS 9032-08-0) produced by Aspergillus niger strain AE-GN under the EU Food Enzymes Regulation. This procedural update, with a current target completion date of 5 February 2028 and a clock stop expected until late April 2026, signals a multi-year authorisation process that food and ingredient manufacturers should monitor when planning future enzyme use and product formulations.

22 Apr 2026, 16:46open.efsa.europa.euEuropean Union

EEA Joint Committee Decision 255/2025 Adds 2025 EU Feed Additive Regulations to Annex I to the EEA Agreement

EEA Joint Committee Decision 255/2025 updates Annex I of the EEA Agreement to incorporate a package of 14 2025 EU feed additive regulations, with entry into force from 6 December 2025 and publication in April 2026. This extends EU feed additive authorisation, renewal and correction measures for enzymes, microbial products, essential oils and vitamin additives to operators in Iceland and Norway (but not Liechtenstein), aligning their feed and premix compliance conditions with the latest EU regime.

21 Apr 2026, 20:12eur-lex.europa.euEuropean UnionIcelandNorway

EFSA Assesses Safety of Food Enzyme Pectin Lyase From Aspergillus luchuensis LC‑07

EFSA’s food enzymes panel has issued a 2026 opinion concluding that pectin lyase from non-genetically modified Aspergillus luchuensis LC-07 does not raise safety concerns for its intended use in juice, plant extract and related food manufacturing processes in Europe. This strengthens the regulatory basis for EU authorisation of this enzyme under the food enzymes framework, signalling that manufacturers can rely on it where needed provided exposures stay within the assessed margins of safety.

21 Apr 2026, 13:56efsa.onlinelibrary.wiley.comEuropean Union

EFSA Opens Consultation on Extension of Use for L-Ascorbate Oxidase Food Enzyme in the EU

EFSA has opened an EU public consultation from 30 March to 20 April 2026 on extending the authorised uses of the food enzyme L-ascorbate oxidase derived from Cucurbita pepo and Cucurbita moschata. This signals a potential future broadening of permitted applications for this enzyme under the EU food enzymes framework, so food and ingredient manufacturers should monitor the process and consider contributing data or comments.

21 Apr 2026, 11:56open.efsa.europa.euEuropean Union

EFSA Concludes No Safety Concerns For Food Enzyme Glucan 1,4‑α‑Maltotetraohydrolase From GM Bacillus Licheniformis DP‑Dzf95

EFSA has issued a positive safety opinion for the food enzyme glucan 1,4‑α‑maltotetraohydrolase, confirming its safety for use in EU food manufacturing. This assessment removes a primary regulatory barrier, allowing manufacturers to advance plans for its integration into food processing while ensuring compliance with allergenicity and safety standards.

9 Apr 2026, 17:36efsa.europa.euEuropean Union

EFSA Receives Application to Modify Glutaminase Food Enzyme (Bacillus licheniformis, NZYM-JQ)

EFSA has commenced a safety review for a modification to the authorized food enzyme glutaminase produced by Bacillus licheniformis. Manufacturers should track this assessment as it may result in revised specifications or usage conditions for enzyme preparations in the European market.

5 Apr 2026, 18:50open.efsa.europa.euEuropean Union

EU EFSA Panel Evaluates Extension Of Use For Food Enzyme Glucan 1,4‑α‑Maltohydrolase (NZYM‑SD)

EFSA has issued a positive safety opinion for extending the use of the food enzyme glucan 1,4-alpha-maltohydrolase to five food manufacturing processes including plant-based milk analogues. This assessment clears a major technical hurdle for expanded market access and provides regulatory certainty for manufacturers using this enzyme in diverse food categories.

2 Apr 2026, 17:04efsa.onlinelibrary.wiley.comEuropean Union

Japan MAFF Amends Pesticides Control Act Ministerial Standards for Phytase-Based Feed Calculations

Japan updated the Pesticides Control Act ministerial standards in March 2026 to align phytase-based feed calculation cross-references with current feed additive regulations. This technical correction ensures regulatory consistency for compound-feed formulations and requires manufacturers to update internal compliance documentation and calculation tools.

1 Apr 2026, 18:26kanpo.go.jpJapan

EFSA Consults on Extension of Use of Alpha-Amylase Food Enzyme (GM Bacillus licheniformis NZYM-AV)

EFSA is consulting on the expanded use of alpha-amylase derived from genetically modified Bacillus licheniformis through April 2026. Successful authorization would broaden market access for this enzyme in food processing while requiring updates to formulation compliance and labeling.

28 Mar 2026, 20:30open.efsa.europa.euEuropean Union

EFSA Consults on Extension of Use for Food Enzyme Endo-1,4-β-Xylanase (Bacillus licheniformis NZYM-CE)

EFSA has launched a consultation on extending the permitted uses for the food enzyme endo-1,4-beta-xylanase produced through genetic modification. Stakeholders should assess the proposed application to anticipate changes in authorization conditions that will impact food improvement agent compliance and EU market access.

28 Mar 2026, 20:30open.efsa.europa.euEuropean Union

EFSA Adopts Opinion on Extension of Use of Cellulase Food Enzyme From GM Trichoderma reesei AR-852

EFSA issued a positive safety opinion in March 2026 supporting the expanded use and revised levels for cellulase enzymes derived from genetically modified sources. This scientific clearance facilitates the formal authorization of broader applications across the food and beverage sectors, including brewing and juice production.

28 Mar 2026, 18:21doi.orgEuropean Union

EU EFSA Updates Safety Evaluation Of Cellulase Food Enzyme From GM Trichoderma reesei AR-852

EFSA has issued a positive safety opinion for the expanded use and revised concentration levels of cellulase from GM Trichoderma reesei in food manufacturing. This scientific endorsement facilitates the formal EU authorization process, enabling broader application and updated use levels for food processing operations.

28 Mar 2026, 17:03efsa.europa.euEuropean Union

EU EFSA Registers Intake of Application to Modify Phospholipase C Food Enzyme (Bacillus licheniformis NZYM-VR)

EFSA has formally registered an application to modify the authorization for the food enzyme phospholipase C produced by Bacillus licheniformis. This initiates a technical safety review that could lead to updated usage specifications or market access conditions for food and beverage manufacturers.

28 Mar 2026, 17:01open.efsa.europa.euEuropean Union

EFSA Intake of Application for Alpha-Amylase Food Enzyme From GM Komagataella Phaffii

EFSA has initiated the formal safety assessment for a new alpha-amylase food enzyme produced from genetically modified microorganisms. Authorization would expand the portfolio of approved processing aids while establishing the specific purity and safety standards required for EU market access.

28 Mar 2026, 09:36open.efsa.europa.euEuropean Union

South Korea MFDS Consults On Draft Safety Review For GM Microorganism-Derived Cellulase Food Additive

South Korea is reviewing the safety of a cellulase food additive derived from genetically modified microorganisms with a consultation closing in April 2026. Successful assessment would provide a regulatory pathway for biotech-derived enzymes in the food sector, necessitating rigorous scientific data alignment for market entry.

27 Mar 2026, 20:06mfds.go.krSouth Korea

EFSA Consultation on Authorisation of Endo-1,4-Beta-Xylanase Feed Additive (Trichoderma reesei KCCM 8037) for All Pigs and Avian Species

EFSA has launched a public consultation on the authorization of endo-1,4-beta-xylanase as a feed additive for pigs and poultry through March 2026. This marks a key step toward EU market entry, requiring producers to validate that safety and efficacy profiles align with zootechnical additive requirements.

27 Mar 2026, 07:53open.efsa.europa.euEuropean Union