Organophosphate Pesticides

EU Researchers Evaluate Chlorpyrifos Developmental Toxicity Using NAM-Based Systematic Review

An EU research team has published an open-access systematic review using new approach methodologies to characterise chlorpyrifos’ developmental and neurotoxic effects across human, rodent, avian, and fish models. The work strengthens the mechanistic case behind existing chlorpyrifos restrictions and illustrates how NAM- and AOP-based evidence can be integrated into next-generation regulatory risk assessments for pesticides and related organophosphates.

28 Apr 2026, 17:47link.springer.comNetherlandsEuropean Union

Japan Consults on Adding Chlorpyrifos to POPs Pesticide Ban List Under Pesticides Control Act

Japan is consulting in April–May 2026 on a draft joint MAFF/MOE ordinance that would add chlorpyrifos to the pesticide ban list under the Pesticides Control Act. This will align Japan with the Stockholm POPs listing by formally prohibiting sale and use of chlorpyrifos-based pesticides and closing off any future route to reintroduce these products.

24 Apr 2026, 09:45public-comment.e-gov.go.jpJapan

Canada PMRA Publishes Project Plan for Cumulative Health Risk Assessment of Organophosphate Pesticides (REV2026-01)

Health Canada has launched a multi-year cumulative risk assessment for 29 organophosphate pesticides with a proposed decision targeted for early 2030. This comprehensive evaluation signals a shift toward stricter aggregate exposure standards that may lead to significant use restrictions or lowered residue limits for food imports.

5 Apr 2026, 06:14canada.caCanada

Japan Opens Public Comment on CSCL Class I Listing of LC-PFCAs, PFCA-Related Substances, Chlorpyrifos and MCCPs

Japan is moving to ban the manufacture and import of LC-PFCAs, chlorpyrifos, and medium-chain chlorinated paraffins by late 2026 under the Chemical Substances Control Law. Companies must urgently identify these substances in global supply chains to ensure compliance with upcoming prohibitions on both chemical mixtures and finished articles.

2 Apr 2026, 16:56public-comment.e-gov.go.jpJapan

California Approves TMDLs for Organophosphate Pesticides and Toxicity in Lower Salinas River Watershed

California finalized water quality limits for chlorpyrifos, diazinon, and malathion in the Lower Salinas River watershed, effective February 2026. Agricultural and municipal operators face stricter discharge compliance requirements, signaling continued regulatory tightening for organophosphate pesticides in sensitive regions.

28 Mar 2026, 20:29waterboards.ca.govUnited States

Welsh Study Finds Veterinary Ectoparasiticides (Imidacloprid, Fipronil and Diazinon) Above Safe Levels in Rivers

A new environmental study identifies significant contamination of Welsh rivers by veterinary pesticides from pet treatments and sheep dips exceeding safety thresholds. This evidence strengthens the case for stricter regulatory oversight of pet care product authorizations and may lead to new restrictions on down-the-drain chemical disposal pathways.

28 Mar 2026, 18:39sciencedirect.comUnited Kingdom

Hawaii Bill SB671 Proposes Ban on Certain Dangerous Pesticides on State Lands

Hawaii is advancing legislation to ban glyphosate, dicamba, and other high-profile pesticides on all state-owned lands and facilities. This move signals a shift toward stricter localized chemical management that will require contractors to adopt alternative substances for state-managed infrastructure and landscaping.

22 Mar 2026, 14:08capitol.hawaii.govUnited States

New Zealand EPA Publishes Q2 2025–26 Hazardous Substances Application Performance Report

New Zealand has revoked approvals for the herbicide DCPA and advanced its reassessment pipeline for high-concern pesticide groups. Impacted firms must finalize disposal by June 2026 and anticipate further regulatory tightening for synthetic pyrethroids and neonicotinoids.

19 Mar 2026, 19:27epa.govt.nzNew Zealand

New Zealand EPA Seeks Feedback on Restricting Stockholm POPs Chlorpyrifos, MCCPs and LC-PFCAs

New Zealand is consulting on banning or strictly limiting chlorpyrifos, MCCPs, and LC-PFCAs by December 2026 to align with Stockholm Convention obligations. Businesses must audit supply chains across electronics, automotive, and textiles to manage accelerated phase-outs or secure time-limited exemptions for essential uses.

18 Mar 2026, 18:53epa.govt.nzNew Zealand

EU RASFF Flags Chlorpyrifos MRL Exceedance in Limes from Brazil

EU authorities have initiated a product recall for Brazilian limes following the detection of chlorpyrifos residues exceeding maximum residue limits. This enforcement signals heightened scrutiny of agricultural imports and reinforces the need for stringent pesticide screening and supplier compliance audits.

12 Mar 2026, 11:18webgate.ec.europa.euEuropean UnionFranceBrazil

Greece Publishes January 2026 Pesticide Residue Monitoring Results for Plant-Origin Foods

Greece published its January 2026 pesticide residue monitoring results, confirming border rejections for non-compliant imports from India and Egypt. Rigorous enforcement against chlorpyrifos and neonicotinoids highlights the critical need for pre-export testing and supply chain audits to mitigate market access risks for agricultural products.

6 Mar 2026, 12:40minagric.grGreece

Rechtbank Gelderland Forfeiture Order for Violations of the Plant Protection Products and Biocides Act

A Dutch court has ordered a 1.6 million EUR profit confiscation for the illegal trade and document forgery of unauthorized plant protection products. This ruling signals intensified enforcement against bulk trade and re-export schemes, requiring companies to provide rigorous proof of destination to claim EU authorization exemptions.

13 Feb 2026, 12:55uitspraken.rechtspraak.nlNetherlands

Japan To Designate Chlorpyrifos, MCCPs And Long-Chain PFCAs As Class I Substances Under CSCL

Japan will ban the manufacture and import of chlorpyrifos, MCCPs, and long-chain PFCAs by late 2026 under the Chemical Substances Control Law. Companies must immediately audit supply chains and accelerate substitution efforts to ensure continued market access for a broad range of industrial and consumer goods.

13 Feb 2026, 07:53meti.go.jpJapan

California DPR Submits Chlorpyrifos Use Summary to Assembly Under SB 86 (6 January 2026)

California's Department of Pesticide Regulation has submitted its statutory chlorpyrifos use summary to the state legislature as of January 2026. This reporting maintains legislative focus on usage trends and phase-out progress for the organophosphate, signaling sustained oversight and potential for future restrictive measures.

12 Feb 2026, 14:55clerk.assembly.ca.govUnited States

California Assembly Introduces AB 1603 Requiring Public Posting of Chlorpyrifos Quarterly Reports

California AB 1603 proposes requiring the public posting of quarterly reports on granular chlorpyrifos usage and exposure data. This shift toward transparency increases reputational and legal risks for users as application locations and exposure levels become accessible to advocacy groups and the public.

20 Jan 2026, 12:45leginfo.legislature.ca.govUnited States

Malaysia Proposes Amendments to Pesticide MRLs in Food Regulations 1985 (G/SPS/N/MYS/71)

Malaysia has proposed extensive updates to pesticide Maximum Residue Limits in food, with a WTO comment period open until March 10, 2026. Impacted businesses should audit supply chains for 19 newly regulated substances and prepare for the total removal of residue allowances for trichlorfon, monocrotophos, and methamidophos.

12 Jan 2026, 15:45docs.wto.orgMalaysia

Oklahoma HB 3013 Proposes Pesticide Limits For Medical Marijuana Testing

Oklahoma HB 3013 introduces mandatory pesticide testing and Maximum Residue Limits for medical marijuana production batches, targeting a November 2026 effective date. Operators must integrate these seventy specific chemical thresholds into quality control and laboratory protocols to maintain market access and mitigate recall risks.

12 Jan 2026, 15:35oklegislature.govUnited States

Uruguay DGSA Proposes Chlorpyrifos Use Restrictions, Allowing Limited Uses in Maize and Sorghum

Uruguay is proposing a near-total ban on chlorpyrifos-based pesticides by January 2026, restricting use to specific pests in maize and sorghum. Agrochemical suppliers and agricultural operators must accelerate the transition to alternative pest management solutions as market access for chlorpyrifos significantly contracts.

31 Dec 2025, 14:36docs.wto.orgUruguay

California OEHHA Requests Carcinogenicity Data on Ethoprop for Proposition 65 Delisting Review

California is re-evaluating the carcinogenicity status of ethoprop under Proposition 65 following updated federal assessments that suggest a lower risk profile. A successful delisting would remove mandatory warning and labeling obligations for products containing this substance, reducing compliance burdens and litigation risks in the state.

23 Dec 2025, 15:46oehha.ca.govUnited States

Study: Pesticide Exposure Linked to Neurodevelopmental Effects in Children

A 2024 scoping review has reinforced the causal link between early-life exposure to organophosphate and pyrethroid pesticides and impaired neurodevelopmental outcomes in children. This evidence is likely to trigger more stringent global residue limits and accelerate the adoption of cumulative risk assessment models by regulatory authorities.

5 Dec 2025, 13:44innospecsustainability.comGlobal