The Great Britain framework for the classification, labelling and packaging of substances and mixtures, which establishes mandatory classification and labelling (GB MCL) requirements following the UK's withdrawal from the EU.
Foresight tracks GB CLP developments and surfaces the alerts most likely to matter before they turn into missed deadlines, recalls, or escalation work.
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Last updated
11 May 2026, 19:00
Source-backed regulatory and guidance signals tracked by Foresight, with the newest developments first.
Great Britain HSE Technical Report On GB MCL Acute Toxicity For Chlorophacinone
In April 2026 the UK Health and Safety Executive issued an Article 37 technical report confirming very high acute toxicity classifications and ATE values for chlorophacinone under the GB CLP Regulation, while recommending that its existing reproductive, repeated-exposure and aquatic hazard categories in the GB MCL entry are retained. Although the updated mandatory GB MCL entry reflecting these ATEs has not yet been adopted, the report signals that GB suppliers of chlorophacinone-based rodenticide products should expect a binding classification aligned with the RAC opinion and prepare for mixture reclassification and label and SDS updates once the decision is finalised.
United KingdomGB CLP Agency Technical Report Recommends Updated Classification for Hydrogen Peroxide Solution (CAS 7722-84-1)
In April 2026 the GB CLP Agency issued an Article 37 technical report recommending updated mandatory classification and labelling for hydrogen peroxide solution, aligning Great Britain with the latest EU RAC opinion on its acute toxicity, oxidising and aquatic hazards. This non-binding assessment signals likely tightening of GB hazard labelling for a widely used oxidising and biocidal active substance, so manufacturers and downstream users should prepare for future label, SDS and risk-management updates once the MCL is formally adopted.
United KingdomGB CLP Agency Issues Article 37 Technical Report on Synthetic Amorphous Silica (CAS 112945-52-5; 112926-00-8)
In April 2026 the UK Health and Safety Executive issued an Article 37 technical report declining, for now, to adopt ECHA’s proposed STOT RE 1 classification for synthetic amorphous silica under Great Britain’s CLP regime. This signals a targeted Article 37A mandatory classification proposal to come, so GB users and producers of synthetic amorphous silica should anticipate a possible GB-specific classification outcome and plan for potential future changes to labelling and risk management.
United KingdomUK Modifies Chemicals Rules with 2026 Amendments to CLP, BPR and PIC
The UK has adopted the Chemicals (Health and Safety) Regulations 2026 (SI 2026/484), entering into force on 21 May 2026 and overhauling how GB CLP, GB BPR and GB PIC operate, including removal of the GB notification database, new fast-track MCL procedures and revised biocides and PIC provisions. This creates binding changes for GB manufacturers, importers, downstream users, biocidal product authorisation holders and exporters, who must adjust classification workflows, plan for automatic extension of certain active substance approvals to 31 July 2031 and ensure export compliance with the streamlined GB PIC and POPs alignment regime.
United KingdomHSE Launches Survey On Potential Changes To GB CLP Regulation
In April 2026 the UK Health and Safety Executive opened a voluntary survey on potential amendments to the GB CLP chemical classification and labelling regime for Great Britain and Northern Ireland. The findings will shape impact assessments and future consultations on incorporating recent EU CLP measures, so affected supply chain actors should assess likely operational and labelling impacts ahead of the 31 May 2026 response deadline.
United KingdomGB CLP Agency Recommends Updated Classification for Clethodim
In March 2026, the GB CLP Agency issued a technical report recommending stronger mandatory classification and labelling for the herbicide clethodim under the GB CLP Regulation. If adopted, this will add self-reactive and repeated-exposure organ toxicity classes and upgrade clethodim’s aquatic hazard, tightening labelling and risk management obligations for GB formulators and users of products containing this active substance.
United KingdomGreat Britain HSE Technical Report Supports Repr. 1B GB MCL Entries for p‑Cymene and Cyclamal Group
In March 2026, Great Britain’s HSE published an Article 37 technical report supporting Repr. 1B reproductive toxicity classifications for p-cymene and four related “cyclamal” fragrance substances under the GB CLP framework. If these GB MCL entries are adopted, manufacturers and importers using these ingredients in mixtures will face tighter classification, labelling, and mixture-assessment obligations and may need to reformulate or adjust supply-chain disclosures ahead of future compliance dates.
United KingdomGB CLP Agency Proposes Updated Mandatory Classification For Metam‑Sodium And Metam‑Potassium
In March 2026 the GB CLP Agency published an Article 37 technical report proposing a significantly strengthened GB mandatory classification for metam-sodium and metam-potassium under the UK CLP Regulation. If adopted, these changes would tighten chronic, carcinogenic, reproductive and aquatic hazard classifications, likely triggering GB-specific updates to labels, safety data sheets and risk management for metam-based plant protection products and downstream uses.
United KingdomGB HSE Article 37 Technical Report on GB CLP Classification of 1,3‑Diphenylguanidine (CAS 102-06-7)
HSE, acting as the GB CLP Agency, has issued a March 2026 Article 37 technical report recommending a new GB mandatory classification and labelling entry for 1,3‑diphenylguanidine (CAS 102-06-7) aligned with the ECHA RAC opinion. If implemented, this would classify the substance as a CMR and multi-endpoint hazard under GB CLP, tightening labelling and risk-management expectations for rubber and other industrial users ahead of a future GB MCL list update.
United KingdomHSE Proposes GB Mandatory Classification of Bisphenol F as Repr. 1B (H360F)
In March 2026 the UK Health and Safety Executive issued an Agency Opinion proposing a GB mandatory classification of bisphenol F (CAS 620-92-8) as Reproductive toxicity Category 1B with hazard statement H360F under the GB CLP Regulation. This aligns GB with EU and Northern Ireland, modestly increases COSHH-driven workplace duties, and creates a clear trigger for potential future UK REACH Annex 17 restrictions and SVHC authorisation decisions on bisphenol F, even though current UK and EEA use appears limited.
United KingdomGreat Britain HSE Agency Opinion Proposes Revised GB MCL for Bronopol (CAS 52-51-7)
In March 2026 the UK Health and Safety Executive issued an Agency Opinion proposing a revised mandatory GB CLP classification for bronopol, aligning Great Britain’s mandatory labelling with the existing EU harmonised classification. Once implemented this will standardise hazard communication and workplace controls for bronopol-containing biocidal, cosmetic, and industrial products in GB and may influence future product approvals, so companies using the substance should prepare to update labels, safety data sheets, and risk assessments when the GB MCL enters into force.
United KingdomGreat Britain HSE Agency Opinion Proposes GB Mandatory Classification and Labelling for 6PPD (N-1,3-Dimethylbutyl-N'-Phenyl-p-Phenylenediamine)
In March 2026 the UK HSE issued an Agency Opinion proposing a GB mandatory classification and labelling for 6PPD as a reproductive toxicant, skin sensitiser and very toxic aquatic substance. If adopted, this GB MCL will align 6PPD’s status with the EU, drive relabelling and SDS updates, and could trigger future UK REACH restrictions or SVHC listing that tyre, rubber and lubricant supply chains need to anticipate.
United KingdomGreat Britain CLP Agency Proposes Repr. 1B Classification for Tincalconite (CAS 12045-88-4)
Great Britain is set to classify tincalconite as a Category 1B reproductive toxicant, harmonizing mandatory classification standards with the European Union. This designation will trigger automatic consumer market restrictions under UK REACH and necessitate immediate updates to product labeling and workplace safety protocols.
United KingdomGreat Britain HSE Publishes New Batch of GB MCL Agency Opinions
The UK Health and Safety Executive has published a new batch of GB MCL Agency Opinions proposing updated mandatory classifications for various industrial and biocidal substances. These proposals signal upcoming changes to labelling and safety data sheet requirements that will necessitate early impact assessments and supply chain adjustments.
United KingdomGreat Britain: HSE Proposes Not To Classify Rapeseed Oil (CAS 8002-13-9)
The UK HSE has formally proposed maintaining the unclassified status for rapeseed oil under GB CLP following a comprehensive hazard assessment. This confirmation provides long-term regulatory certainty and ensures continued alignment with EU standards, avoiding any new labeling burdens or supply chain friction.
United KingdomGB HSE Issues Agency Opinion Proposing GB MCL For 3,5-Dimethylpyrazole
The UK Health and Safety Executive has formally proposed a mandatory classification for 3,5-dimethylpyrazole as a reproductive toxicant and organ-specific toxin. This move will likely trigger UK REACH restrictions on consumer sales and require immediate updates to safety data sheets and workplace risk assessments across multiple industrial sectors.
United KingdomGB HSE Agency Opinion Proposes Repr. 1B GB MCL For Colemanite
The UK HSE has proposed a mandatory Repr. 1B reproductive toxin classification for colemanite to align Great Britain’s hazard standards with the EU. Impacted firms must prepare for mandatory relabeling and stricter workplace controls while anticipating future UK REACH restrictions on consumer use and SVHC listing.
United KingdomGreat Britain: HSE Agency Opinion Proposes Skin Sens. 1B Classification for Thermally Treated Garlic Juice
The UK Health and Safety Executive has proposed a new mandatory classification for thermally treated garlic juice as a Skin Sensitiser Category 1B. This development triggers mandatory label and safety data sheet updates and may restrict the authorization of amateur-use biocidal products.
United KingdomGreat Britain HSE Agency Opinion Proposes Carc. 1B GB MCL for EDTMP‑H
The UK HSE has proposed a mandatory Carc. 1B classification for EDTMP-H, aligning Great Britain with existing EU hazard standards. This designation will trigger stricter workplace safety requirements and likely lead to future UK REACH restrictions on consumer applications and potential SVHC listing.
United KingdomGreat Britain HSE Proposes Carc. 1B GB MCL for EDTMP-CaNa (CAS 85480-89-3)
The UK HSE has proposed a mandatory Carc. 1B classification for EDTMP-CaNa, aligning Great Britain with EU standards for this widely used chemical. This change will trigger consumer use restrictions under UK REACH and require significant updates to safety data sheets and product labeling across multiple sectors.
United KingdomThese are just a few of the most recent GB CLP alerts. Foresight tracks every jurisdiction, every day — and surfaces only what affects your portfolio, with full citations and evidence.
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Definition
The Great Britain framework for the classification, labelling and packaging of substances and mixtures, which establishes mandatory classification and labelling (GB MCL) requirements following the UK's withdrawal from the EU.
Industry relevance
GB CLP developments can change product scope, supplier expectations, market access, reporting duties, and risk ownership. Foresight tracks the signals early so teams can respond before obligations become urgent.
Foresight tracking
Foresight monitors official sources, extracts structured regulatory intelligence, and maps alerts to a customer's products, substances, markets, and priorities so teams see the relevant signal with source evidence for review.
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