EPA Approves Trifludimoxazin Herbicide Registrations For Specified Crop Uses

The US Environmental Protection Agency (EPA) posted a final registration decision for trifludimoxazin on 30 June 2026. The decision covers one technical product and five end-use products, including two combinations with saflufenacil.

Trifludimoxazin had previously been registered on 17 May 2021 before those registrations were voluntarily withdrawn. The 2022 application was a new application, rather than the first application for the molecule.

Crop Uses And Risk Assessment

The decision covers specified crop groups, including cereal grains and associated forage, fodder and straw groups excluding rice, alongside maize, soybeans, peanuts, citrus, pome fruit, tree nuts and legume vegetables. Permitted uses remain subject to product-specific labels.

EPA’s decision under section 3(c)(5) of the Federal Insecticide, Fungicide, and Rodenticide Act found no dietary or aggregate human-health risks of concern for the assessed uses. It separately identified ecological risks and mitigation requirements, including controls addressing spray drift and runoff.

Existing residue tolerances remained in place; the application did not include a new tolerance petition. The decision describes condition-dependent degradation of the parent substance and its residues.

PFAS Classification Depends On The Definition

Minnesota’s regulatory review, posted on 31 August 2026, explicitly classifies trifludimoxazin as PFAS under Minnesota law. That state classification is separate from EPA’s use-specific federal pesticide registration decision.

The federal docket records when the final memorandum was posted. It does not establish that every individual product registration letter was issued on the same date.