
EFSA Seeks Feedback on Overhaul of Weight of Evidence and Biological Relevance Guidance
EFSA launches consultation on updating its Weight of Evidence and Biological Relevance guidance, aiming to streamline chemical risk assessment practices.


The European Commission has unveiled the EU Chemicals Industry Action Plan, introducing a strategic roadmap and implementation timeline aimed at revitalising the European chemical sector. Announced on 8 July 2025, the initiative includes the sixth Simplification Omnibus and a series of forthcoming proposals and legislative changes that will impact manufacturers, suppliers, regulators, and innovation leaders across the EU.
Spanning from Q3 2025 through to the end of 2026, the timeline marks critical deadlines for regulatory reform, industrial investment, and sustainability transitions.
The Action Plan is structured around four pillars:
At the heart of this strategy is the establishment of a Critical Chemicals Alliance, tasked with coordinating support for vulnerable chemical production sites and substances. Complementing this is an enhanced trade defence framework and new monitoring tools for critical imports.
The Simplification Omnibus introduces targeted changes to the CLP, Fertilisers, and Cosmetics Regulations, offering clarity and cost savings for SMEs and large-scale manufacturers alike.
Q3 2025
Q4 2025
Q1 2026
Q2 2026
Q4 2026
The Commission estimates at least €363 million in annual savings through simplification measures alone. Stakeholders from sectors such as pharmaceuticals, automotive, consumer goods, and packaging are advised to evaluate how the reforms may impact labelling obligations, product development timelines, raw material sourcing, and regulatory approvals.
Initiatives such as the Digital Product Passport and harmonised customs surveillance will tighten compliance expectations while providing transparency throughout supply chains.
Foresight continuously tracks 1000s of sources and maps updates to your portfolio:




EFSA launches consultation on updating its Weight of Evidence and Biological Relevance guidance, aiming to streamline chemical risk assessment practices.

The Netherlands refines its list of potential ZZS chemicals to better align with EU assessments, boosting early detection and regulatory foresight.

EU Court backs bioenergy and plastics taxonomy criteria, rejecting ClientEarth’s challenge. Decision clarifies sustainability definitions under the EU Taxonomy Regulation.
Subscribe to Foresight Weekly and get the latest insights on regulatory changes affecting chemical compliance.
Free forever. Unsubscribe anytime.
Read by professionals at