
ChemSec Adds Neurotoxicants to SIN List in Landmark Step for EU Chemicals Regulation
ChemSec updates the SIN List with neurotoxicants, spotlighting brain-damaging chemicals and urging EU regulators to act swiftly on these hidden threats.


A new global science-policy panel on chemicals, waste and pollution was officially established on 20 June 2025 in Uruguay. The Intergovernmental Science-Policy Panel on Chemicals, Waste and Pollution (ISP-CWP) aims to strengthen regulatory frameworks and provide evidence-based guidance, significantly impacting manufacturers, regulators, and stakeholders across the chemicals value chain.
The ISP-CWP fills a longstanding gap in global environmental governance, complementing existing bodies such as the IPCC and IPBES. It will deliver scientific assessments to support policies for the sound management of chemicals and waste, particularly benefiting developing countries lacking technical capacity.
Its core functions include horizon scanning for emerging risks, evaluating chemical-related threats, facilitating knowledge exchange, and building capacity across sectors. This is particularly relevant as endocrine disruptors, persistent pollutants, and hazardous substances remain key concerns for industries from plastics to pharmaceuticals.
The panel’s scope is global, covering regulatory impacts on production, import, and disposal activities. UNEP will serve as the interim secretariat, with a trust fund established to finance operations.
For manufacturers, the ISP-CWP is poised to influence national and international regulatory agendas. Companies can expect earlier signals of upcoming restrictions or authorisation requirements, driven by scientific consensus. This offers both a compliance challenge and an opportunity to align products with sustainability and safety goals.
Stakeholders in waste management, logistics, public health, and environmental monitoring should also prepare for tighter coordination as data sharing and policy integration increase across borders. Small island states and emerging economies have already voiced strong support for capacity building through the panel’s structure.
The first plenary session is scheduled no later than June 2026. During this session, the panel will finalise rules of procedure, define its work programme, and settle outstanding issues such as observer participation and scope language.
UNEP has invited governments and donors to provide financial and logistical support. Membership is open to all UN states expressing intent before 8 December 2025.
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