United StatesTSCA

EPA Seeks Peer Reviewers For Phthalates Risk Evaluation Under TSCA

The EPA is requesting nominations for qualified scientists to review the risk evaluations of five phthalates. The peer review, set for spring 2025, will support regulatory actions under TSCA. Candidates must submit their details by 2 January 2025.

Published in December 2024. Dates, deadlines and stages may have changed since.

Dr Steven Brennan

2 min readAI-drafted, expert reviewed

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The US Environmental Protection Agency (EPA) is inviting nominations for peer reviewers to assess the scientific risk evaluations of five phthalates—BBP, DBP, DEHP, DIBP, and DCHP. The evaluations, integral to regulatory decisions under the Toxic Substances Control Act (TSCA), will undergo public peer review in spring 2025.

Purpose Of The Peer Review

The EPA aims to ensure that the risk evaluation of phthalates, chemicals linked to male reproductive health issues and found in various consumer products, meets the highest scientific standards. Phthalates have been detected in food and human blood, with prenatal exposure linked to conditions like “phthalate syndrome,” affecting male reproductive development​​.

Reviewer Requirements

The agency is looking for experts with qualifications in toxicology, risk assessment, biostatistics, epidemiology, or related fields. Selected reviewers will evaluate the methodologies and scientific approaches used in draft evaluations.

Nominees must also provide financial disclosures to ensure impartiality, avoiding any conflict of interest in the peer review process.

Public Participation And Deadlines

Public engagement is a key component. Stakeholders will have access to technical support documents, expected to be released incrementally over the next six months, ensuring adequate time for review and feedback. The deadline for nominations is 30 days from the Federal Register notice publication, with submissions directed to the EPA Science Advisory Committee on Chemicals (SACC)​​.

Impact On Regulatory Decisions

The SACC's review will influence EPA's final risk evaluations and risk management measures for these phthalates. The agency emphasises the importance of diverse scientific perspectives in shaping policy decisions.

Questions about this change

What are phthalates, and why are they being reviewed by the EPA?

Phthalates are chemicals used in various consumer products. The EPA is evaluating their risks due to evidence of their impact on human health, particularly male reproductive health.

How can I nominate a candidate for the EPA peer review panel?

Nominations must be emailed to SACC@epa.gov within 30 days of the Federal Register notice publication. Nominees should have expertise in relevant scientific fields and disclose potential financial conflicts of interest.

Dr Steven Brennan

CEO and co-founder of Foresight, and a co-opted member of ECHA's Committee for Socio-economic Analysis. He holds a PhD in chemical engineering.

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