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AICIS Publishes Chemical Assessments Impacting Personal Care And Agricultural Sectors

The latest AICIS assessments set clear compliance boundaries for chemicals used in cosmetics and agriculture. Professionals across the supply chain must now ensure all handling, reformulation, and use of these substances meet AICIS-defined conditions.

Published in July 2025. Dates, deadlines and stages may have changed since.

Dr Steven Brennan

2 min readAI-drafted, expert reviewed

Cosmetics

On 16 July 2025, the Australian Industrial Chemicals Introduction Scheme (AICIS) released new chemical assessment statements under section 37 of the Industrial Chemicals Act 2019. The updates concern two substances widely used in personal care and agricultural products, potentially affecting compliance duties across supply chains in cosmetics, farming, and specialty chemicals.

One assessment covers Heptanoic acid, 1,1′,1′′-(1,2,3-propanetriyl) ester (CAS: 620-67-7), commonly used in personal care products. The second pertains to D-Glucopyranose, oligomeric, citrates, C10-16-alkyl glycosides, sodium salts (CAS: 1693733-02-6), an ingredient in soil conditioning agents. Both assessments conclude that risks to human health and the environment can be managed if introduced as defined.

Substance Risks And Use Cases Explained

The triglyceride-based Heptanoic acid ester is imported into Australia either neat or pre-formulated at up to 33% concentration in cosmetics. While it is a skin irritant in undiluted form, it does not meet the classification thresholds for hazards under the Globally Harmonized System (GHS). Its use requires standard engineering controls during reformulation but poses no risk to consumers under typical usage.

By contrast, the alkyl glycoside salt used in agriculture is classified under GHS as toxic to aquatic life (Acute Category 2). However, it is not persistent, bioaccumulative or systemically toxic. Its application is restricted to soil conditioning at a diluted dose of up to 0.01%, with a maximum of 48.8 g/hectare.

Industry Implications And Compliance Outlook

For chemical introducers, these published statements impose clear parameters for lawful introduction, including volume caps, concentration limits, and use conditions. Under section 100 of the Act, all introducers must monitor for new hazard information and submit annual declarations.

Reformulators, contract manufacturers, and agribusiness operators must assess their exposure pathways and update safety data sheets, while downstream users such as logistics providers and distributors should ensure transport and storage align with the new classifications and guidance.

Action Points For Compliance Professionals

Stakeholders should now:

  • Confirm product formulations align with the defined scope of assessment.
  • Review site-specific engineering controls or PPE protocols for reformulation.
  • Monitor for updates via the AICIS website or subscribe to chemical alerts.

Questions about this change

What does the AICIS assessment of heptanoic acid ester mean for cosmetic manufacturers?

The AICIS assessment allows continued use of Heptanoic acid ester in personal care products up to 33%, provided it's reformulated safely. No hazard classification under GHS applies, but PPE and ventilation are recommended during reformulation.

How should businesses report updates related to these AICIS-assessed chemicals?

Under section 100 of the Industrial Chemicals Act 2019, introducers must report any new information suggesting increased hazard or risk. This includes adverse effects, changes in use, or new toxicological data. Reports should be submitted promptly via the AICIS Business Services portal to maintain compliance.

Dr Steven Brennan

CEO and co-founder of Foresight, and a co-opted member of ECHA's Committee for Socio-economic Analysis. He holds a PhD in chemical engineering.

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