Isothiazolinones
A family of broad-spectrum biocides and preservatives (including MIT, CIT, BIT, and OIT) widely used in consumer and industrial products, subject to strict concentration limits and restrictions due to skin sensitisation and environmental toxicity.
Foresight tracks Isothiazolinones developments and surfaces the alerts most likely to matter before they turn into missed deadlines, recalls, or escalation work.
Current activity
Steady
In line with the prior 8-week baseline
3-month trend
Latest alerts below
Last updated
25 March 2026, 21:42
Latest Isothiazolinones alerts
The most recent regulatory and guidance signals tracked by Foresight
EU BPC Issues Opinions on Minor Changes to Union Authorisations for SOPUROXID and C(M)IT/MIT & Glutaraldehyde Formulations
The EU Biocidal Products Committee has approved minor changes to Union authorisations for SOPUROXID and C(M)IT/MIT & Glutaraldehyde formulations. These opinions enable classification downgrades and expanded packaging options, while highlighting the rigorous technical equivalence standards required for manufacturing site updates.
California DPR Lists Pesticide Products Entering Evaluation Process (Volume 2026-11)
California DPR has initiated technical evaluations for several pesticide and disinfectant products, including new registrations and label amendments for insecticides and wood preservatives. These reviews signal upcoming shifts in permitted label claims and market availability for specific biocidal and antimicrobial formulations in California.
GB HSE Highlights Biocides Active Substance Renewal Submission Deadlines
The UK HSE has issued a critical reminder for 550-day renewal submission deadlines for several biocidal active substances, including MIT and OIT, under the GB BPR. Businesses must ensure renewal applications are supported by the 2026-2027 deadlines to prevent the loss of market access for biocidal products and treated articles in Great Britain.
EU – ECHA Updates Biocidal Products Review Programme Notifications For Hydrogen Peroxide And Other Active Substances
ECHA updated the BPR Review Programme list in March 2026, setting new application deadlines for hydrogen peroxide and chlorine dioxide while confirming several unsupported substance/PT combinations. Companies must initiate phase-out plans for biocidal products containing unsupported substances like BIT or Geraniol in specific uses to mitigate market exit risks.
Netherlands RIVM Updates Children's Exposure to Isothiazolinones and Parabens
The Dutch RIVM has confirmed that aggregate exposure of children to isothiazolinone and paraben preservatives in personal care products remains within safe levels. This finding stabilizes the near-term regulatory outlook for these preservatives while reinforcing the use of refined aggregate modeling as the standard for future safety assessments.
EU BPC Issues February 2026 Biocides Opinions Including Ethanol Approval Support
ECHA’s Biocidal Products Committee has supported the approval of ethanol for disinfectants and the renewal of hydrochloric acid, while rejecting DMDMH for preservative uses (February 2026). These opinions signal upcoming European Commission decisions, requiring manufacturers to prepare for new product authorisation requirements or potential market withdrawals for non-approved substances.
EU Draft Implementing Decision on Non-Approval of Terbutryn, BIT and Related Biocidal Substances
The EU has proposed the non-approval of Terbutryn, BIT, and a formaldehyde-releasing substance for specific biocidal product types. Impacted businesses must prepare for the phase-out of these substances in biocidal products and treated articles, requiring urgent substitution planning and supply chain assessments.
ECHA Updates BPR Review Programme List Of Notifications (20 February 2026)
ECHA’s updated BPR Review Programme list sets critical 2026-2027 application deadlines for hydrogen peroxide and chlorine dioxide while confirming phase-outs for several other substances. Impacted businesses must secure dossier submissions for supported substances or execute withdrawal strategies for products containing unsupported actives like BIT and ADBAC.
Northern Ireland: HSE Highlights EU BPR Deadlines For Selected Biocidal Active Substances
Approaching EU BPR deadlines in Northern Ireland require active substance renewal submissions by August 2026 and product authorisations by February 2027. Impacted companies must secure these approvals to prevent the mandatory withdrawal of disinfectants, insecticides, and treated articles from the market.
China NMPA Issues Notice Listing 50 Batches of Non-Compliant Cosmetics (2026 No. 6)
China's NMPA has flagged 50 batches of cosmetics for non-compliance following the 2025 national sampling inspection, targeting issues in hair dyes, sunscreens, and shampoos. This enforcement action underscores the regulator's focus on formula consistency and ingredient safety, requiring manufacturers to tighten quality control and ensure alignment between registered dossiers and physical products.
Japan Consults on Draft ISHA Amendments on Chemical Label/SDS Scope and Carcinogen Record-Retention
Japan is consulting on draft amendments to the Industrial Safety and Health Act (ISHA) to expand the list of substances requiring mandatory labelling and Safety Data Sheets (SDS) by April 2028. The proposal also introduces a 30-year record-retention requirement for carcinogenic substances, signaling a long-term shift toward stricter occupational health oversight and hazard communication for industrial chemicals.
UK HSE Reminds of Non-Approval Planned For BIT And Terbutryn (Product Type 9) Under EU BPR
The EU is moving toward non-approval of 1,2-benzisothiazol-3(2H)-one (BIT) and terbutryn for use in product type 9 (fibre, leather, rubber and polymerised materials preservatives) due to a lack of industry support in the Review Programme. Companies supplying treated articles or biocidal products in Northern Ireland must prepare for market withdrawal and identify alternative preservatives to avoid supply chain disruption.
Netherlands Ctgb Publishes Registrations for Plant Protection Products and Biocides (Stcrt. 2026, 712)
The Dutch Ctgb has published updated registrations and authorization details for plant protection products and biocides (January 2026). Impacted businesses must verify their specific product listings to ensure uninterrupted market access and compliance with Dutch-specific use and labeling requirements.
HSE Highlights EU BPR Active Substance Renewal Deadlines for Northern Ireland
The UK HSE has issued a reminder for upcoming EU BPR active substance renewal deadlines in Northern Ireland, with the first critical submission window closing in March 2026. Companies must coordinate with suppliers or consortia to ensure renewal applications are submitted to ECHA 550 days before expiry to maintain market access for biocidal products and treated articles.
ECHA Updates BPR Treated Articles Article 94 List With New Hydrogen Peroxide And TCDO AS-PT Combinations
ECHA has updated the BPR Article 94 list for treated articles, adding new notifications for hydrogen peroxide and chlorine dioxide and clarifying phase-out dates for rejected substances. Manufacturers should audit biocidal treatments in their products to ensure alignment with upcoming 2026-2027 dossier deadlines and avoid market access disruptions for withdrawn combinations.
GB HSE Highlights Upcoming GB BPR Active Substance Renewal Submission Deadlines
The UK HSE has confirmed renewal application deadlines for multiple biocidal active substances, including peracetic acid and isothiazolinones, between March 2026 and June 2027. Companies must submit renewal applications at least 550 days before expiry to avoid the mandatory withdrawal of biocidal products and treated articles from the GB market.
Japan MHLW Proposes Adding 36 Controlled Chemicals to ISHA Labelling and SDS Obligations
Japan is expanding mandatory labelling and SDS obligations under the Industrial Safety and Health Act to include 36 additional substances, including several PFAS. Manufacturers and importers should audit Japanese portfolios for these substances to ensure compliance with hazard communication requirements ahead of the April 2028 enforcement date.
Commission Decision C(2025) 8879: Revised EU Ecolabel Criteria for Paints and Varnishes
The European Commission adopted revised EU Ecolabel criteria for paints and varnishes in December 2025, significantly tightening restrictions on hazardous substances and VOCs. Companies must audit formulations against new limits for isothiazolinones and titanium dioxide to retain market differentiation through the EU’s premier voluntary sustainability mark.
EU Authorises CMIT/MIT Solvent-Based Biocidal Product Family
The EU has granted a 10-year Union authorisation for the 'CMIT/MIT SOLVENT BASED' biocidal product family, valid until February 2033 for fuel and oil preservation. Companies must navigate specific geographical exclusions and strict professional-use restrictions to ensure compliant distribution and application across the European market.
ECHA Releases Revised Agenda for Biocides Working Group Meeting IV-2025
ECHA's Biocides Working Group is reviewing key active substances and product family authorisations throughout December 2025. Impacted firms should monitor discussions on substances like CMIT/MIT and PAA-based disinfectants to anticipate shifts in authorization conditions or technical guidance.
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