Good Laboratory Practice (GLP)

Norway Opens Consultation On Amendments To Regulation On Use Of Animals In Experiments

Norway is consulting on stricter animal welfare standards for scientific experiments to align with EU Delegated Directive 2024/1262. Research facilities and life sciences firms must review laboratory protocols for zebrafish, cephalopods, and rodents to ensure compliance with updated housing and euthanasia requirements.

28 Mar 2026, 16:59hoering.mattilsynet.noNorway

UK Home Office Issues 2026 Code of Practice for Care and Accommodation of Animals in Science

The UK Home Office has published a new mandatory Code of Practice for the care and accommodation of animals used in science, effective June 25, 2026. Establishments must update internal compliance protocols and infrastructure to meet these revised minimum standards for housing, equipment, and husbandry.

27 Mar 2026, 18:41gov.ukUnited Kingdom

UK MHRA Sets Out Approach To Medicines Using Non-Animal Methods

The UK MHRA has introduced a formal framework and a 2026 pre-review mechanism to facilitate the use of non-animal testing methods (NAMs) in medicines regulation. This provides a clear pathway for developers to de-risk animal-free evidence packages, signaling a long-term regulatory pivot that prioritizes scientific justification over traditional animal-based testing protocols.

26 Mar 2026, 19:23gov.ukUnited Kingdom

Michigan CRA Files Formal Complaints Against Infinite Chemical Analysis Labs (Jackson, Michigan)

Michigan's Cannabis Regulatory Agency has filed formal complaints against a safety compliance laboratory for failing to adhere to approved testing protocols and quality standards. This enforcement action signals heightened oversight of laboratory data integrity and ISO/IEC 17025 compliance, increasing risk for businesses relying on third-party testing for market access.

26 Mar 2026, 12:20michigan.govUnited States

European Commission States Retracted Glyphosate Review Does Not Affect EU Risk Assessment

The European Commission confirmed in March 2026 that the retraction of a glyphosate safety review paper has no impact on the substance's current EU approval or risk assessment. This decision provides regulatory certainty for glyphosate-based products, signaling that the EU’s assessment framework prioritizes primary regulatory data over secondary academic literature.

26 Mar 2026, 11:44europarl.europa.euEuropean Union

ECHA Issues Best-Practice Guidance on Fish Sexual Development Test (OECD TG 234)

ECHA has issued new technical guidance on conducting Fish Sexual Development Tests (OECD TG 234) to standardize the identification of endocrine-disrupting properties under REACH, BPR, and CLP. Companies should align testing protocols with these best practices to ensure data acceptance during regulatory substance evaluations and hazard classifications.

26 Mar 2026, 11:37echa.europa.euEuropean Union

South Korea MFDS Issues 2026 Basic Plan for Management of Medical Device Non-Clinical Testing Institutions

South Korea's MFDS has released its 2026 oversight plan for medical device non-clinical testing institutions to align with international reliability standards. Manufacturers and labs should review the plan to ensure readiness for 2026 inspection cycles and maintain the integrity of safety data required for market access.

22 Mar 2026, 10:32mfds.go.krSouth Korea

US FDA Issues Draft Guidance on Use of New Approach Methodologies in Drug Development

The US FDA has issued draft guidance establishing a validation framework for New Approach Methodologies (NAMs) to modernize safety assessments in drug development. This signals a regulatory transition toward non-animal testing, requiring sponsors to align validation and reporting protocols with FDA evidentiary standards to ensure regulatory acceptance.

21 Mar 2026, 18:27fda.govUnited States

New York Assembly Bill A10564 Proposes Restricting Toxicology Testing To State-Authorized Laboratories

New York Assembly Bill A10564 proposes to restrict toxicology testing certifications to personnel employed in state-authorized clinical laboratories. Impacted facilities must review personnel qualifications and laboratory authorizations to ensure compliance with the proposed 12-month implementation timeline.

14 Mar 2026, 15:15assembly.state.ny.usUnited States

EU/ECHA Article 46 Decision Requires Fish Endocrine Studies for Tonalide (AHTN)

ECHA has mandated registrants of Tonalide (AHTN) to submit specific fish endocrine studies by May 2029 to clarify environmental safety concerns. This data request signals potential future regulatory escalation, including SVHC identification or EU-wide restrictions, if endocrine-disrupting properties are confirmed.

12 Mar 2026, 13:41echa.europa.euEuropean Union

ECHA Orders Amphibian Endocrine Disruption Study for Bis(2-Propylheptyl) Phthalate Under REACH

ECHA has mandated an extended amphibian study for Bis(2-propylheptyl) phthalate (DPHP) by November 2028 to investigate potential environmental endocrine-disrupting properties. This decision signals increased regulatory scrutiny for high-volume phthalates used in PVC and coatings, with results likely determining future SVHC identification or restriction measures.

12 Mar 2026, 13:41echa.europa.euEuropean Union

Canada Issues Significant New Activity Notice No. 22294 for Stannate Nanomaterial (CAS 12027-96-2)

Canada has implemented Significant New Activity (SNAc) Notice No. 22294 for Stannate (CAS 12027-96-2), effective March 7, 2026. Manufacturers must now submit detailed notifications before using the substance as a nanomaterial or in aerosolized consumer products, signaling heightened regulatory scrutiny of inhalation and nano-scale risks.

11 Mar 2026, 14:03gazette.gc.caCanada

ECHA Science Seminar on INVITES‑IN Tool for Assessing Internal Validity of In Vitro Studies

ECHA has introduced INVITES-IN, a new methodological tool designed to standardize the assessment of reliability and bias in in vitro studies used for chemical risk assessments. This development signals a shift toward more rigorous validation of non-animal data, potentially accelerating the acceptance of alternative testing methods in regulatory filings.

10 Mar 2026, 14:40echa.europa.euEuropean Union

New Jersey DEP Clarifies FY27 Laboratory Certification Renewal Requirements

New Jersey has finalized the FY27 environmental laboratory certification renewal cycle, mandating electronic submissions by April 1, 2026. Rigorous enforcement of personnel reporting and updated method parameters requires immediate compliance reviews to avoid certification downgrades and loss of testing authorization.

9 Mar 2026, 17:03dep.nj.govUnited States

South Korea MFDS Launches 2026 "Lab Friends" Technical Support Programme For Testing Laboratories

South Korea's MFDS has opened applications for its 2026 "Lab Friends" programme, providing technical support and ISO/IEC 17025 mentoring for private testing laboratories through March 2026. Companies should verify that their contract laboratories are participating to ensure continued alignment with national testing standards and robust quality assurance for regulated products.

9 Mar 2026, 14:42mfds.go.krSouth Korea

US HHS/SAMHSA Updates Certified Laboratory List for Federal Workplace Drug Testing

The US HHS has updated the list of certified laboratories authorized to perform federal workplace drug testing as of March 2026. Regulated employers and federal agencies must ensure their testing providers remain on this accredited roster to maintain compliance with mandatory drug-screening guidelines.

6 Mar 2026, 12:57federalregister.govUnited States

European Pharmacopoeia Commission Clarifies Recombinant Factor C Integration and Future Innovation Pathways

The European Pharmacopoeia has integrated Recombinant Factor C (rFC) as a validated, animal-free method for bacterial endotoxin testing, following the mandatory phase-out of the rabbit pyrogen test. This provides a clear regulatory pathway for pharmaceutical manufacturers to transition to synthetic reagents, requiring updates to quality control strategies and safety risk assessments.

16 Feb 2026, 19:26edqm.euEuropean Union

European Commission Publishes Factual Summary of GLP Directives Evaluation Consultation

The European Commission has released stakeholder feedback on the evaluation of the Good Laboratory Practice (GLP) Directives, confirming broad support for the framework's role in ensuring data integrity. Future policy direction is likely to focus on reducing administrative burdens and aligning standards with digital technologies and emerging non-animal testing methods.

16 Feb 2026, 19:08eur-lex.europa.euEuropean Union

SETAC Technical Issue Paper — Recommended Minimum Reporting Information for Eco‑Transcriptomics Studies

SETAC has published new global reporting standards for eco-transcriptomics studies to improve data transparency and comparability in environmental risk assessments. While non-binding, these criteria signal a shift toward standardized New Approach Methodologies (NAMs) that will likely influence future regulatory data requirements and chemical safety evaluations.

15 Feb 2026, 16:56setac.orgGlobal

OECD Opens Second Commenting Round on Draft Revised Guidance for Pesticide Residue Analytical Methods

The OECD is finalizing harmonized global standards for pesticide residue testing, with a public consultation open until March 16, 2026. This update will align validation requirements across member countries, simplifying the regulatory path for global pesticide registrations and international trade compliance.

15 Feb 2026, 16:47oecd.orgGlobal