Eye Irritation / Damage

Reversible or irreversible damage to the eye from chemical exposure — a GHS hazard class driving labelling and protective equipment requirements.

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Last updated

3 May 2026, 14:43

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Latest Eye Irritation / Damage developments

Source-backed regulatory and guidance signals tracked by Foresight, with the newest developments first.

ECHA RAC Adopts Harmonised CLP Classification Opinion for Bis(pentane-2,4-dionato)calcium

ECHA’s CLH registry shows that its Risk Assessment Committee has adopted a harmonised classification opinion for bis(pentane-2,4-dionato)calcium under the EU CLP Regulation, covering acute oral toxicity, serious eye damage and strong skin sensitisation hazards. Although this classification is not yet implemented in Annex VI, companies using this substance in the EU should expect a future ATP and begin aligning internal classification, labelling and worker-protection measures to reflect the forthcoming harmonised hazards.

echa.europa.euEuropean UnionEuropean Union

ECHA Opens CLP Harmonised Classification Consultation For Maleic Acid

From 20 April 2026 ECHA is consulting on a proposal to tighten the harmonised CLP classification of maleic acid, upgrading it from irritant to corrosive to skin and seriously damaging to eyes while confirming acute oral toxicity. If adopted, this will force updates to classifications, labelling, and safety data sheets for maleic acid and its mixtures, with knock-on impacts on packaging, workplace controls, and downstream product portfolios.

echa.europa.euEuropean UnionEuropean Union

Illinois SB4045 Would Prohibit Lachrymatory Agents And Require Approval Of Pepper Spray Formulations

Illinois Senate Bill 4045 would ban most uses of tear gas and other lachrymatory agents in Illinois, require state approval of pepper spray formulations, and create new reporting, database, and enforcement mechanisms for chemical irritants. If enacted, this would fundamentally change law enforcement crowd-control options and the state’s pepper spray market, forcing reformulation, new IDPH rulemaking, and heightened liability and data transparency for chemical agent deployments.

ilga.govUnited StatesUnited States

EU CLH Intention Announced for 1,1,3,3-Tetramethyldisiloxane

Belgium has notified ECHA of its intention to propose harmonised classification for 1,1,3,3-tetramethyldisiloxane, with a formal dossier expected by mid-2027. Proposed classifications for reproductive toxicity and irritation signal future tightening of hazard communication requirements and potential downstream restrictions for this siloxane.

echa.europa.euEuropean UnionEuropean Union

EU EFSA Publishes Scientific Opinion On Renewal Of Clinacox 0.5% (Diclazuril) For Chickens

EFSA has issued a favorable scientific opinion supporting the renewal of the feed additive diclazuril for poultry. This assessment secures a path for continued market access while reinforcing the need for rigorous worker protection and potential future environmental data submissions.

efsa.onlinelibrary.wiley.comEuropean UnionEuropean Union

EU ECHA BPC Adopts Opinion on Approval of Ethanol for Product Type 2 Disinfectants

The ECHA Biocidal Products Committee has recommended the approval of ethanol for small-surface disinfectants, setting strict purity standards and consumer safety requirements. Although ethanol currently avoids exclusion status, ongoing pressure for more stringent hazard classification signals potential future restrictions and the need for long-term formulation planning.

echa.europa.euEuropean UnionEuropean Union

Great Britain: OPSS Issues Product Safety Report on Hania Bridal Henna Paste Containing Phenol

UK authorities have mandated the withdrawal of a cosmetic product from the market due to the presence of phenol, a prohibited substance under the GB Cosmetics Regulation. This enforcement action highlights the increasing scrutiny on ingredient compliance and the immediate operational risks associated with using prohibited substances in consumer products.

gov.ukUnited KingdomUnited Kingdom

EU Commission Authorises Patchouli Essential Oil Feed Additive for All Animal Species Under Implementing Regulation (EU) 2026/528

EU Implementing Regulation 2026/528 authorises patchouli essential oil as a sensory feed additive for all animal species effective April 2026. Manufacturers must update labels and safety protocols to meet new identification and worker protection standards by the October 2026 transitional deadline.

eur-lex.europa.euEuropean UnionEuropean Union

EU Commission Adopts Implementing Regulation Authorising Xanthan Gum Feed Additive for Most Animal Species

The EU has transitioned xanthan gum feed additive from legacy open-ended approval to a 10-year time-limited authorization effective April 2026. Operators must align formulations with new species-specific maximum levels and update labels to include mandatory PPE and stability instructions.

eur-lex.europa.euEuropean UnionEuropean Union

European Commission Adopts Confidentiality Decision on Biochem Zinc(II)–Betaine Complex Feed Additive Application

The European Commission has finalized a confidentiality decision for the zinc(II)–betaine complex feed additive, signaling the final stages of the market authorization process. Animal nutrition businesses should prepare for imminent approval and the subsequent implementation of specific use conditions and labeling requirements for this zinc source.

ec.europa.euEuropean UnionEuropean Union

ECHA RAC Opinion on Harmonised CLP Classification for 2-Amino-2-Methylpropanol (CAS 124-68-5)

ECHA's Risk Assessment Committee has recommended upgrading the harmonised classification of 2-amino-2-methylpropanol to include reproductive toxicity Category 1B and skin corrosion. Formal adoption by the European Commission would mandate label updates and potentially trigger automatic bans in consumer products or stricter workplace safety requirements.

echa.europa.euEuropean UnionEuropean Union

EU Commission Adopts Implementing Regulation (EU) 2026/460 Renewing Thiamine Feed Additives For All Animal Species

The European Union has renewed the authorization for thiamine-based feed additives until 2036, introducing stricter purity standards and new hazard classifications for worker safety. Manufacturers must update workplace safety protocols and labeling to address newly identified sensitization risks while managing phased inventory transitions through 2028.

eur-lex.europa.euEuropean UnionEuropean Union

Minnesota HF 3745 Proposes Ban on Tear Gas Chemical Orthochlorobenzalmalononitrile

Minnesota is moving to prohibit the manufacture and sale of the tear gas chemical orthochlorobenzalmalononitrile and all products containing it. Businesses face an immediate loss of market access upon enactment and must prepare for mandatory inventory disposal under state environmental oversight.

revisor.mn.govUnited StatesUnited States

EFSA Assesses Safety and Efficacy of Zinc-Lysinate Sulfate Feed Additive for All Animal Species

EFSA has confirmed the efficacy of zinc-lysinate sulfate as a feed additive while highlighting critical data gaps regarding consumer safety and marine environmental impacts. Companies should prepare for potential delays in market authorization and stringent workplace safety requirements to mitigate respiratory and dermal exposure risks.

efsa.europa.euEuropean UnionEuropean Union

EU EFSA FEEDAP Panel Issues Opinion on Renewal of Coated Granulated Cobalt(II) Carbonate Feed Additive

EFSA has flagged safety data gaps for coating agents in cobalt(II) carbonate feed additives, stalling a definitive safety conclusion for consumers and the environment. This development signals potential regulatory delays or the imposition of stricter handling and labeling requirements for specific granulated product formulations.

efsa.europa.euEuropean UnionEuropean Union

EFSA FEEDAP Opinion on Renewal and Extension of Belfeed B MP/ML Feed Additive for All Poultry Species and Swine

EFSA has issued a positive safety opinion for the renewal and expanded use of the Belfeed B MP/ML feed additive across all poultry and swine species. This paves the way for formal EU market re-authorization while signaling stricter requirements for microbial contamination monitoring and worker protection against respiratory sensitization.

efsa.europa.euEuropean UnionEuropean Union

EFSA FEEDAP Panel Issues Opinion on Renewal of Benzoic Acid (4d210, VevoVitall®) Feed Additive Authorisation for Porcine Species

EFSA issued a scientific opinion in February 2026 supporting the renewal of benzoic acid as a feed additive for porcine species, confirming its safety for animals and consumers. While existing usage levels remain unchanged, businesses must maintain strict occupational safety protocols and personal protective equipment to manage the substance's irritant properties.

efsa.onlinelibrary.wiley.comEuropean UnionEuropean Union

EU CLP: Estonia Submits CLH Intention for 2,2,2-Trifluoroethanol

Estonia has notified ECHA of its intention to propose a harmonised classification for 2,2,2-trifluoroethanol, including its designation as a Category 1B reproductive toxin. A formal Repr. 1B classification would trigger mandatory labelling updates and likely lead to downstream restrictions under REACH and other sector-specific regulations for consumer and professional products.

echa.europa.euEuropean UnionEuropean Union

Minnesota Senate Bill SF 3772 Proposes Ban On Orthochlorobenzalmalononitrile Tear Gas Compound

Minnesota introduced legislation in February 2026 to ban the manufacture, sale, and use of the tear gas compound orthochlorobenzalmalononitrile. If enacted, businesses must immediately terminate commercial operations involving this substance and prepare for mandatory disposal of existing inventory.

revisor.mn.govUnited StatesUnited States

China Drafts GB Standards To Align With GHS Rev. 11

China is updating eight mandatory GB 30000 standards to align national chemical hazard classification and labeling with UN GHS Revision 11. Businesses should prepare for mandatory reassessments of chemical portfolios and significant updates to safety data sheets and product labels to ensure continued market access.

std.samr.gov.cnChinaChina

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Topic context

How to read Eye Irritation / Damage regulatory activity

Definition

What is Eye Irritation / Damage?

Reversible or irreversible damage to the eye from chemical exposure — a GHS hazard class driving labelling and protective equipment requirements.

Industry relevance

Why it matters

Eye Irritation / Damage developments can change product scope, supplier expectations, market access, reporting duties, and risk ownership. Foresight tracks the signals early so teams can respond before obligations become urgent.

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How Foresight monitors it

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