The U.S. Chamber of Commerce has called for targeted TSCA reform to address delays and regulatory uncertainty, warning that current implementation challenges risk undermining innovation, investment, and supply chain resilience. In comments submitted on 30 March 2026 to the House Energy and Commerce Committee, the Chamber urged lawmakers to modernise the Toxic Substances Control Act while maintaining strong health and environmental protections.
A central issue in the TSCA reform debate is the Environmental Protection Agency's handling of new chemical approvals under Section 5. According to the Chamber, EPA has "routinely exceeded" the statutory 90-day review period, often relying on repeated suspensions of the review clock, reducing predictability for businesses.
The submission calls for enforceable timelines, the use of conditional approvals where risks can be appropriately managed, and limits on consent orders and Significant New Use Rules to evidence-based cases. It also proposes accountability mechanisms if deadlines are missed, including requiring decisions within defined backstop periods or, in some cases, deemed approvals based on the administrative record.
For manufacturers and downstream users, particularly SMEs, predictable access to new chemistries remains critical for innovation and competitiveness.
The Chamber emphasises that TSCA reform should reinforce risk-based evaluations grounded in real-world conditions. This includes assessing chemicals based on specific conditions of use rather than aggregating exposures across all uses, and recognising existing protections such as personal protective equipment.
Greater coordination across federal programmes is also recommended. The proposal highlights that EPA should avoid duplicative regulation and may rely on determinations from other frameworks, including the SNAP programme and OECD authorities, where conditions of use are comparable.
Structured interagency consultation, including with OSHA, is identified as a way to improve technical rigour and alignment on exposure limits.
The TSCA reform discussion also addresses complex substances such as UVCBs and regulatory approaches to PFAS and persistent, bioaccumulative and toxic substances. The Chamber calls for clearer statutory criteria to determine when substances qualify as existing chemicals, reducing duplicative reviews.
It further warns that overly broad or uncertain application of regulatory authorities could create supply chain disruption, particularly where chemistries are used in critical sectors such as energy, medical devices, infrastructure, and advanced manufacturing.
The submission also highlights the need to clarify and consistently apply exemptions for replacement parts in long-lifecycle products, such as aerospace and industrial equipment, to avoid unnecessary operational and cost impacts.
Beyond risk evaluation, TSCA reform proposals aim to streamline reporting and reduce duplication. Recommendations include limiting overlapping obligations for manufacturers and importers, excluding articles from certain reporting requirements, and aligning thresholds with OSHA hazard communication standards.
Modernisation of EPA's Central Data Exchange is also proposed to improve reporting accuracy and reduce administrative burden.
TSCA reform proposals seek to restore predictability and efficiency in US chemical regulation while maintaining robust safety standards. By reinforcing risk-based approaches, improving interagency coordination, and reducing duplication, the measures aim to support innovation, strengthen supply chains, and enhance global competitiveness.
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