Key takeaway
What this development means
The U.S. Environmental Protection Agency (EPA) has released its final risk evaluation for Tris(2-chloroethyl) Phosphate (TCEP), determining that the chemical poses serious health risks, including kidney cancer, nervous system damage, and fertility issues. TCEP, used as a flame retardant in products like paints and textiles, also threatens the environment, particularly aquatic ecosystems. Workers, consumers, and vulnerable groups are most at risk from exposure. The EPA plans to implement regulatory actions to mitigate these dangers, following the evaluation under the Toxic Substances Control Act (TSCA). Public involvement will be encouraged during the risk management process.
What are the main health risks associated with exposure to Tris(2-chloroethyl) Phosphate (TCEP)?
The EPA's final risk evaluation for TCEP identifies significant health risks, including kidney cancer, damage to the nervous system, and reproductive harm. Workers in industries that handle TCEP, consumers exposed to products containing the chemical, and vulnerable groups like pregnant women and children are particularly at risk. Long-term exposure, especially through inhalation or ingestion of dust from treated fabrics or foam, poses the greatest danger.
How will the EPA address the risks posed by Tris(2-chloroethyl) Phosphate (TCEP)?
The EPA plans to introduce regulatory actions under the Toxic Substances Control Act (TSCA) to mitigate the unreasonable risks associated with TCEP. This will likely include restrictions on its use in manufacturing and consumer products, as well as limits on its environmental release. Public participation will be sought during the regulatory process, allowing stakeholders to provide feedback on proposed rules aimed at reducing TCEP’s health and environmental impacts.
Source basis: https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/risk-evaluation-tris2-chloroethyl-phosphate-tcep
Health Risks of TCEP Exposure
The EPA's final risk evaluation identified TCEP as a carcinogenic substance with severe health impacts. Notably, TCEP exposure can lead to kidney cancer, damage to the nervous system, and reproductive harm. The assessment specifically highlighted the elevated risks for vulnerable groups, including pregnant women, children, and fenceline communities—populations living near facilities that release TCEP. Workers in industries handling TCEP, such as paint manufacturing, face increased risks from direct contact or inhalation of the chemical.
TCEP's Use and Widespread Exposure
TCEP (CASRN 115-96-8) is predominantly used as a flame retardant and plasticizer in aerospace equipment, paints, and coatings. Despite a reported reduction in its manufacturing from 2016 to 2020, TCEP remains prevalent in various commercial and consumer products. The EPA’s evaluation covered 21 conditions of TCEP use, identifying seven that pose unreasonable risks to workers, such as those in paint and coating industries, and three consumer-related risks, particularly in fabrics, textiles, and foam products. Consumers may unknowingly inhale or ingest TCEP-laden dust, exacerbating health concerns.
Environmental Concerns of TCEP
Beyond human health, TCEP presents substantial risks to the environment, particularly aquatic ecosystems. Fish and other aquatic organisms are at risk due to TCEP contamination in water bodies. Subsistence fishers and indigenous communities, whose diets rely heavily on fish, are especially vulnerable to these risks. The chemical's ability to bioaccumulate in aquatic life raises alarms for long-term environmental health.
Regulatory Actions and Public Involvement
Following the findings, the EPA will initiate risk management efforts under the Toxic Substances Control Act (TSCA) to mitigate the health and environmental dangers posed by TCEP. A proposed rule is expected to follow, with public comments welcomed throughout the process. In previous steps, the EPA had already proposed a Significant New Use Rule (SNUR) in June 2023, which aims to prevent any new uses of TCEP without thorough EPA review.