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Regulatory Assessment of Linear Aliphatic Dicarboxylic Acids (C≥8) and Their Salts

General
22
October 2024
•
400
Dr Steven Brennan
ECHA's latest report on linear aliphatic dicarboxylic acids finds no immediate need for regulatory actions, ensuring their safe use in various industries.
Manufacturing lubricants
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A recent report from the European Chemicals Agency (ECHA) has concluded that no immediate regulatory risk management (RRM) actions are required for the group of substances known as linear aliphatic dicarboxylic acids (C≥8) and their salts. The comprehensive assessment focused on potential human health and environmental hazards, ultimately determining that these chemicals pose no significant risks under current usage conditions.

ECHA's Detailed Findings

The ECHA assessment reviewed a range of linear aliphatic dicarboxylic acids, including well-known chemicals such as sebacic acid, azelaic acid, and dodecanedioic acid. These substances are widely used across various industries, including cosmetics, lubricants, adhesives, and pharmaceuticals. The report evaluated the potential for both human exposure and environmental release, concluding that these chemicals do not present significant hazards under their current uses.

The assessment highlighted that these substances are mainly used in consumer and professional applications, which could lead to widespread dispersive use. Despite this, the evaluation found no critical hazards related to carcinogenicity, mutagenicity, reproductive toxicity, or endocrine disruption.

No Regulatory Action Needed

Based on the information available, ECHA recommended no immediate need for further regulatory action at the EU level. The chemicals demonstrated no significant long-term environmental hazards such as persistent bioaccumulation or toxicity. Additionally, human health concerns like skin or eye irritation were minimal and deemed manageable under proper self-classification by manufacturers.

Sebacic acid and hexadecanedioic acid, two prominent substances in this group, were flagged for compliance checks. However, these checks were precautionary, as no severe risks have been identified.

Supporting Information

The report also reviewed a variety of industrial uses. These substances are employed in everything from paints and coatings to cosmetic formulations and pharmaceuticals, showing their versatility. Despite their widespread use, exposure levels for both humans and the environment appear to be within safe limits, reinforcing the conclusion that no immediate regulatory interventions are required.

The lack of significant health or environmental risks from linear aliphatic dicarboxylic acids highlights the safety of their current use. However, ECHA will continue to monitor these substances for any future developments or new data that could alter their regulatory status.

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