
EU Overhauls Drug Precursor Regulation to Combat Designer Chemicals and Ease Compliance
EU launches new Regulation on drug precursors, targeting designer chemicals and reducing admin burden with digital systems for chemical industry compliance.
The EPA released its proposed guidance on 2 December 2024, aimed at streamlining ESA evaluations for new active ingredients, new uses, and ongoing registration reviews of antimicrobial pesticides. This effort complies with the Pesticide Registration Improvement Act of 2022 (PRIA 5) and supports the 2022 ESA Workplan.
While PRIA 5 focuses on outdoor applications, the EPA expands the guidance to include indoor uses with potential environmental exposure. For instance, antimicrobial agents in industrial water treatment that discharge into aquatic systems are also covered.
To enhance ESA analyses, the guidance recommends:
By predicting risks and suggesting mitigations early, the guidance aims to reduce delays during ESA consultations with the U.S. Fish and Wildlife Service and the National Marine Fisheries Service.
The EPA invites feedback from stakeholders, including industry professionals and conservation groups, to refine the guidance. Submitted comments will influence the final document, slated for release by December 2025.
The guidance aims to balance wildlife conservation with the practical needs of antimicrobial pesticide users, ensuring ESA compliance without unnecessary regulatory burdens.
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EU launches new Regulation on drug precursors, targeting designer chemicals and reducing admin burden with digital systems for chemical industry compliance.

AICIS proposes key changes to its Categorisation Guidelines for 2026. Industry professionals are invited to comment on high-hazard updates and regulatory clarifications.

The EU has delayed labelling and classification deadlines under the CLP Regulation to reduce compliance pressure. Changes affect fuel labelling and online sales.
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