Key takeaway
What This Development Means
UBA’s MICROSOIL project urges a comprehensive update to soil microorganism risk assessments for agricultural chemicals, introducing new functional and structural tests. This shift could reshape regulatory compliance strategies, strengthen environmental safeguards, and better align chemical use with sustainability goals.
What is the main outcome of the MICROSOIL project?
The MICROSOIL project recommends adding bacterial function and fungal structure tests to chemical risk assessments, alongside developing community fingerprinting methods, to better capture the real-world impacts of pesticides, biocides, and veterinary pharmaceuticals on soil microorganisms.
Why is antibiotic resistance a concern in soil microorganism assessments?
Current veterinary pharmaceutical assessments may overlook the potential for antibiotic resistance to develop in soil bacteria. This poses environmental and public health risks, as resistant bacteria could transfer into food systems or water supplies, undermining antimicrobial effectiveness.
Source basis: https://www.umweltbundesamt.de/publikationen/correctly-assessing-the-performance-threats-of
The German Environment Agency (UBA) has called for significant updates to the risk assessment of soil microorganisms exposed to agricultural chemicals, including pesticides, biocides and veterinary pharmaceuticals. The recommendations follow the MICROSOIL project, which found that current testing methods fail to capture the full scope of risks, potentially overlooking impacts such as antibiotic resistance in soil bacteria.
Expanding The Risk Framework
The existing risk assessment for plant protection products (PPPs) relies heavily on the OECD 216 nitrogen turnover test. While useful, this laboratory method does not address all potential threats to the soil microbial community. The MICROSOIL project identified five alternative testing approaches through literature review and scoring, with subsequent laboratory trials across three soils and six test substances.
Key Recommendations
UBA experts propose adding:
- Bacterial function testing using ISO 20130 (enzymatic activity).
- Structural impact assessment for mycorrhizal fungi via ISO 10832.
- Community fingerprinting methods to evaluate broader changes in microbial structure, although these require further refinement.
The study also found that repeated chemical applications, and the presence of multiple substances, can either enhance or reduce microbial degradation capacity, underscoring the complexity of soil-chemical interactions.
Implications For Industry And Regulation
These findings have far-reaching implications for professionals across the manufacturing value chain, including agrochemical producers, regulatory bodies, and food supply chain stakeholders. The omission of antibiotic resistance assessment in current veterinary pharmaceutical testing is a particular concern, given its potential to affect both environmental health and human safety.
The proposed testing enhancements would improve the detection of sub-lethal and structural impacts, enabling more informed regulatory decisions and supporting sustainable soil management practices.
Related Articles

Citizens Omnibus Initiative Targets EU Administrative Burdens
The Citizens Omnibus Initiative extends the EU simplification agenda into rules that affect legally resident citizens, cross-border mobility and Single Market access.

Digital Product Passport Registry Proposal Expands EU Compliance Requirements
A draft EU digital product passport registry rule would set technical and governance requirements for product passport data across multiple regulated sectors.

EU Bisphenols Restriction Proposal Targets PVC, Textiles And Thermal Paper
Germany's planned EU REACH restriction could affect bisphenols in PVC, textiles, thermal paper, leather processing, recycling and second-hand markets.
