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The EU is evaluating HHCB, a common fragrance ingredient, for potential reproductive health risks. Public consultation is underway, which may lead to stricter regulations.
Published in January 2025. Dates, deadlines and stages may have changed since.
2 min readAI-drafted, expert reviewed

The European Union is currently evaluating the reproductive toxicity of 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyran, commonly known as HHCB or Galaxolide. This chemical, widely used in perfumes and personal care products, is under scrutiny due to potential adverse effects on reproductive health, as highlighted in recent studies.
HHCB, also known as Galaxolide, is a synthetic musk used extensively in the fragrance industry. It is found in a variety of consumer products, including perfumes, cosmetics, and cleaning agents. Its popularity stems from its ability to impart a long-lasting scent, making it a staple in many household items.
Recent evaluations have raised concerns about HHCB's impact on reproductive health. Studies indicate that exposure to HHCB may lead to adverse effects on sexual function and fertility. The chemical has been linked to decreased body weight in offspring and potential endocrine-disrupting properties. These findings have prompted regulatory bodies to consider stricter classification and labelling requirements for HHCB.
The European Chemicals Agency (ECHA) has initiated a public consultation to gather comments on the proposed classification of HHCB as a reproductive toxicant. This consultation, open until 28 March 2025, invites stakeholders to provide input on the potential risks associated with HHCB. The outcome could lead to changes in how HHCB is regulated and labelled within the EU.
The fragrance industry is closely monitoring the situation, as any regulatory changes could impact product formulations and market availability. Companies may need to explore alternative ingredients or reformulate products to comply with new regulations. The ongoing evaluation underscores the importance of assessing chemical safety and its implications for consumer health.
Official source
echa.europa.euHHCB, or Galaxolide, is a synthetic musk used in fragrances for its long-lasting scent. It is commonly found in perfumes, cosmetics, and cleaning products, making it a popular choice in the fragrance industry.
HHCB has been linked to reproductive health concerns, including adverse effects on sexual function and fertility. Studies suggest it may disrupt endocrine function, prompting regulatory bodies to consider stricter classification and labelling.

Dr Steven Brennan
CEO and co-founder of Foresight, and a co-opted member of ECHA's Committee for Socio-economic Analysis. He holds a PhD in chemical engineering.
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