
EFSA Seeks Feedback on Overhaul of Weight of Evidence and Biological Relevance Guidance
EFSA launches consultation on updating its Weight of Evidence and Biological Relevance guidance, aiming to streamline chemical risk assessment practices.


The European Union is spearheading a new initiative to tackle the pervasive issue of per- and poly-fluoroalkyl substances (PFAS) in the healthcare sector. Launching in January 2025, this project aims to develop sustainable alternatives to PFAS, reduce emissions, and manage end-of-life disposal, aligning with the EU's Green Deal and Chemicals Strategy for Sustainability.
PFAS are widely used in healthcare products due to their durability and resistance to heat and chemicals. These substances are found in medical devices, packaging, and even in the manufacturing processes of pharmaceuticals. However, their persistence in the environment and potential health risks have raised significant concerns. The EU's initiative seeks to map PFAS applications across the healthcare supply chain and develop safer alternatives without compromising product efficacy or safety.
The initiative encourages collaboration between industry stakeholders, including pharmaceutical companies, healthcare providers, and regulatory bodies like the European Chemicals Agency (ECHA). By fostering public-private partnerships, the project aims to enhance knowledge about PFAS applications and alternatives. This collaboration will also involve testing and validating new materials to ensure they meet regulatory standards.
One of the primary objectives is to reduce PFAS emissions and exposure. The project will explore end-of-life management options, such as recycling and safe disposal, to minimise environmental impact. Additionally, it will focus on developing a database of PFAS alternatives and new disposal processes. These efforts are crucial for protecting both the environment and public health.
The initiative faces challenges, including the complexity of the global supply chain and the need for standardised testing protocols. However, by leveraging industry-academia collaboration, the project aims to overcome these hurdles. The EU's commitment to reducing PFAS usage aligns with broader health and environmental policies, ensuring long-term sustainability and innovation in the healthcare sector.
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