EPA Proposes Registration of New Pesticide Active Ingredient Glycerol Formate for Hospital Use

What is Glycerol Formate?

Glycerol Formate is a new active ingredient composed of three ester forms: glycerol monoformate, diformate, and triformate. It is designed to work as a sporicidal disinfectant for non-porous hard surfaces and a sanitizer for soft surfaces in healthcare facilities such as hospitals, medical premises, and nursing homes. This two-part system combines Glycerol Formate with hydrogen peroxide to create Performic Acid (PFA), the active biocide that disinfects surfaces​​.

EPA’s Evaluation and Risk Assessment

The EPA conducted a thorough evaluation to assess the potential risks and benefits of Glycerol Formate. The proposed use is limited to indoor environments with minimal risk of environmental exposure. The EPA's assessment concluded that the risks to human health are low, with no expected dietary exposures. Glycerol Formate reacts quickly with hydrogen peroxide to form PFA, which then rapidly degrades into water and oxygen, reducing environmental impact​.

Usage Instructions and Safety Precautions

Glycerol Formate is used as part of a two-part system where Part A (containing Glycerol Formate) is mixed with Part B (containing hydrogen peroxide) to generate PFA. The end-use solution is then applied with a wipe to disinfect surfaces. Safety precautions include avoiding direct contact with eyes and skin. The solution must be handled according to label instructions, and the EPA has proposed that it poses no significant risk to healthcare workers when used correctly​​.

Public Participation and Comment Period

The EPA is seeking public comments on the proposed registration of Glycerol Formate. Interested parties can submit their comments through the Regulations.gov website by October 14, 2024. This feedback will contribute to the EPA's final decision regarding the registration of this new active ingredient​.

The proposed registration of Glycerol Formate represents a significant step forward in hospital disinfection, offering a new tool to combat pathogens while minimizing risks to human health and the environment. The EPA's public comment period provides an opportunity for stakeholders to contribute to the final decision.