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ECHA Releases Comprehensive Report on Saccharides

General
2
July 2024
•
450
Dr Steven Brennan
ECHA recommends no immediate regulatory actions for the saccharides group based on the current data.
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The European Chemicals Agency (ECHA) has published an extensive report detailing the regulatory needs assessment for saccharides, a group of substances primarily composed of sugars and carbohydrates. This assessment aims to evaluate the necessity for further regulatory actions for substances within this group.

The report identifies a total of 46 substances grouped under the saccharides category, characterised by the general molecular formula CmH2nOn. These substances include common sugars such as glucose, fructose, sucrose, and lactose, among others. The grouping is based on structural similarity and shared functional uses across various industries.

Key Substances and Uses

  • D-Ribose (CAS: 50-69-1)
  • Glucose (CAS: 50-99-7)
  • Fructose (CAS: 57-48-7)
  • Sucrose (CAS: 57-50-1)
  • Xylose (CAS: 58-86-6)
  • Galactose (CAS: 59-23-4)
  • Lactose (CAS: 63-42-3)
  • D-Mannitol (CAS: 69-65-8)
  • Maltose (CAS: 69-79-4)
  • 1,3-Dihydroxyacetone (CAS: 96-26-4)
  • Trehalose (CAS: 99-20-7)

These substances are widely used in various product categories including washing and cleaning products, cosmetics, pharmaceuticals, perfumes, fragrances, and textile dyes. Many of these substances are also used in food and pharmaceutical industries due to their natural occurrence and functional properties.

Regulatory Assessment and Findings

The regulatory assessment undertaken by ECHA involves a detailed examination of each substance’s potential hazards, both to human health and the environment. The primary aim is to determine whether any substances in this group warrant further regulatory actions to ensure safety and compliance.

Key Conclusions

  1. Human Health Hazard:
    • No significant hazards have been identified for the majority of the substances in the saccharides group.
    • Substances like dihydroxyacetone and L-erythrulose, used in self-tanning products, are noted for their unique application and require specific mention due to their skin interaction properties.
  2. Environmental Hazard:
    • Most saccharides exhibit low environmental hazards due to their high water solubility and biodegradability.
    • One substance, identified by list number 944-860-3, has been self-classified as having chronic aquatic toxicity (Aquatic Chronic 3).
  3. Use and Exposure:
    • The report highlights the widespread use of saccharides in consumer and professional products, leading to significant exposure potential.
    • Despite this widespread use, no immediate regulatory actions are proposed due to the low hazard nature of these substances.

Proposed Actions

ECHA recommends no immediate regulatory actions for the saccharides group based on the current data. However, the agency suggests ongoing monitoring and potential reassessment should new information or concerns arise. The report emphasises the need for continued evaluation, particularly for substances with specific applications like cosmetics.

Industry Impact and Future Directions

The publication of this report provides valuable insights for manufacturers, regulators, and consumers regarding the safety and regulatory status of saccharides. Companies are encouraged to stay informed about the latest regulatory developments and to consider the findings in their strategic planning and product development processes.

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