
ChemSec Adds Neurotoxicants to SIN List in Landmark Step for EU Chemicals Regulation
ChemSec updates the SIN List with neurotoxicants, spotlighting brain-damaging chemicals and urging EU regulators to act swiftly on these hidden threats.


Japan has formally adopted its National Plan of Action for implementing the Global Framework on Chemicals (GFC) in April 2025, signalling a strategic overhaul of its chemical safety policies. This development introduces clear objectives and targets impacting the entire manufacturing value chain—prompting compliance reviews and new strategic considerations across sectors such as health, agriculture, and construction.
The GFC, adopted globally in September 2023 at ICCM5, is a voluntary international initiative aimed at minimising harm from chemicals and waste throughout their lifecycle. Japan’s national implementation, developed through inter-ministerial coordination and public input, integrates 28 global targets with local regulatory frameworks—ranging from the Chemical Substances Control Law to the Act on Waste Management and Public Cleaning.
The plan is structured around five strategic objectives, including strengthening legal frameworks, increasing transparency and data availability, phasing out highly hazardous pesticides, and enhancing stakeholder engagement.
Key mandates for Japan include establishing poison centres nationwide by 2030, expanding GHS labelling implementation, and improving supply chain traceability through tools like chemSHERPA and IMDS. It also encourages voluntary corporate initiatives such as Responsible Care and sustainable chemistry investment.
For industry professionals, the GFC Plan links directly to domestic priorities outlined in the Sixth Basic Environment Plan and the Fifth Circular Economy Plan—amplifying its regulatory weight. Japan’s government will also integrate national indicators aligned with GFC targets and report progress to international partners.
The new plan extends beyond manufacturers, with clear expectations for finance, retail, logistics, and public health entities. Companies are urged to improve risk communication and product disclosure, while financial institutions are advised to reflect chemicals management in ESG reporting.
Local governments are tasked with enforcement support and environmental monitoring. Citizens and NGOs are encouraged to engage in risk awareness and advocacy, while academic institutions are seen as vital for advancing research and informing policy.
Japan will present its implementation strategy at the First Open-Ended Working Group on GFC, scheduled for June 2025 in Uruguay. This move not only consolidates its domestic leadership in chemicals governance but also reinforces its influence in shaping regional and global frameworks.
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