
EFSA Seeks Feedback on Overhaul of Weight of Evidence and Biological Relevance Guidance
EFSA launches consultation on updating its Weight of Evidence and Biological Relevance guidance, aiming to streamline chemical risk assessment practices.


The European Commission has adopted new restrictions on Dechlorane Plus, a widely used flame retardant, by amending Regulation (EU) 2019/1021 on persistent organic pollutants (POPs). This change, announced on 15 May 2025, introduces phased bans and exemptions that directly affect professionals across the chemicals, automotive, aerospace, medical, and electronics sectors.
Dechlorane Plus is a chlorinated flame retardant used in adhesives, tapes, wire harnesses, lubricants, and polymer matrices. Its persistence, bioaccumulation potential, and suspected toxicity led to global regulatory scrutiny. The substance was listed in Annex A of the Stockholm Convention in 2023, triggering the EU's obligation to align its domestic rules under the POPs Regulation.
The European Chemicals Agency (ECHA) and the European Commission have recognised that while certain critical applications exist, the overall goal is to eliminate the use of Dechlorane Plus to protect human health and the environment.
The new EU regulation establishes two thresholds for Dechlorane Plus in products:
Exemptions apply for up to five years, including:
These exemptions allow continued use and servicing of existing equipment and may be reviewed for extension by April 2028.
Stakeholders across the supply chain must assess product formulations, procurement practices, and legacy equipment inventories. The restriction particularly affects OEMs, spare parts suppliers, and end-users in regulated sectors. Risk assessments and substitution planning should begin immediately.
The Commission has indicated that the volume of Dechlorane Plus used in exempted spare parts is minimal, but manufacturers must document usage and ensure traceability to comply with future enforcement.
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